Clinical Research

and it’s development

Used in traditional Indian medicine since 1000 BC, ashwagandha root is a powerful Rasayana—an adaptogen that helps the body navigate physical, biological and chemical stressors.1 This evergreen shrub, which is cultivated in tropical and subtropical areas of Asia, Africa and Europe, is officially known as Withania somnifera (L.) Dunal; the term ashwagandha comes from Sanskrit, combining ‘ashwa’ (horse) and ‘gandha’ (smell) to describe the wet horse smell of roots of the plant.

B.O.T

Natural Remedies leverages its proprietary, Bioactive Optimization Technology (B.O.T.)™ This state-of-theart technology combines the principles of chemistry and biological sciences to deliver a bioactive optimized extract, characterized by high bioactivity at low dose. This approach encompasses full spectrum activity, ensuring the delivery of an ingredient with enhanced efficacy, robust safety profile and with significant impact.

Evidence-based Claims

Energy, Endurance and Stress-relief

Cardiovascular Endurance:

Ashwa 30 significantly increases VO2 max levels in healthy individuals and helps them perform intense exercises for a longer period.

STUDY

Randomized, prospective, double-blind, placebo-controlled clinical trial

SUBJECTS

63 healthy adults; Ashwa 30: 30 mg/d and placebo.

ENDPOINT

Change in cardiovascular endurance, assessed by VO2 max.

Outcomes
↑ VO₂ max
↓ fatigue
↑ EMG activation

Stress Reduction:

Ashwa.30 demonstrates a 38.5% reduction in cortisol levels compared to placebo at day 7, enhancing stress resilience.

STUDY

The randomized, double-blind, placebo-controlled trial

SUBJECTS

40 Healthy adults Ashwa.30 (30 mg/d) and placebo groups

ENDPOINT

Salivary cortisol collected at baseline, day 7 post-treatment, and day 7 post-MAST.

Outcomes
↓ salivary cortisol post MAST
↑ stress resilience

Mechanism of Action: Ashwa.30TM for Stress resilience and Performance Optimization

Adaptogens like Ashwa.30TM help in modulating cortisol levels and supporting physical performance

Inducing the State of Nonspecific Resistance (SNSR)

Modulating cortisol levels

Enhancing aerobic glycolysis, supporting efficient ATP production

Reducing lactic acid accumulation, delaying fatigue

Promoting sustained performance even under physical stress

Small Dose. Big Difference

Adults: 30 mg/ day
Children: 15 mg/ day

Applications

  • Energy and Endurance supplements 
  • Sports nutrition 
  • Stress relief supplements 
  • Functional foods

Dear Colleagues & Friends,

It is widely accepted that herbs and botanicals offer immense health benefits. Traditional systems and practices across the globe have played a key role in offering natural solutions for various health conditions. On the other hand, modern medicines - that are based on chemical drugs also have added significant value to healthcare. Herbs, unlike the chemical drugs, have a complex and largely unknown chemical composition that pose scientific challenges to conduct clinical studies, evaluate safety, decipher the mechanisms of actions and to define and control quality of commercial preparations. In addition, multiple other issues pertaining to herbs need scientific understanding and solutions. These include identification of plants, natural variations of chemical composition of medicinal plants, contaminants, adulterations, analytical challenges, impact of climate change, sustainability, etc. Consumption of herbal products is increasing globally with growing demand for botanical supplements and complementary medicine. At the same time, the scientific work on all the above-mentioned issues has also gained rapid pace during the last two decades. Purpose of this webinar series is to kindle thoughts and discuss the current updates and scientific knowledge available on above mentioned issues with experts.

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