GutGard® and
it’s development
Digestive disturbances are affecting more individuals than ever, largely due to stress and dietary habits (eg: nutritionally lacking, as well as eating quickly, on the run). These factors combine to create a host of issues such as gas and bloating, acid reflux/heartburn, stomach griping, flatulence, diarrhea, cramps, and constipation. And, poor digestion leads to lack of energy, poor sleep, and overall malaise. Upper digestive ailments are also often caused by a bacterial infection, chiefly, Helicobacter pylori.
GutGard® for daily digestive health
GutGard® is a clinically researched, flavonoid-rich, natural bioactive for daily digestive health derived from Glycyrrhiza glabra. GutGard®is standardized to >3.5% glabridin and >10% total flavonoids with glycyrrhizin level to be made <0.5%
GutGard® is the only of its class to offer the advantage of the cache of flavonoids found in licorice. More than 50 flavonoids including isoflavans (glabridin), Isoflavones (example: licoflavone A), Isoflavanones (example: glabrol), chalcones (example: isoliquiritigenin), etc, have been identified in GutGard®by using liquid chromatography-mass spectrometry. Batch to batch consistency of the flavonoid profile is monitored with the help of high-performance liquid chromatography.
Traditional uses 
Licorice has a long, rich use in cultures worldwide; it was even found in the tomb of King Tutankhamun. The dried root of licorice has been used by not only the Egyptians but throughout the populations and cultures of Asia and the Mediterranean regions. The Romans relied on it for numerous ailments. Licorice is recorded in the pharmacopoeias of nations throughout the world.
In the first century AD, the Greek physician Dioscorides used licorice to treat people with stomach and intestinal ulcers (it is known now that many ulcers are caused by Helicobacter pylori).
Licorice was revered by the ancient Egyptians who used it to make tonics that were placed in the canopic jars to accompany them into the afterlife. It is also said that legendary generals Julius Caesar, Alexander the Great, and Napoleon Bonaparte used licorice. In the Eurasian steppe, the Scythian tribes relied on licorice to survive when water was scarce.
GutGard®: Backed by human clinical studies for daily digestive health

Clinical study 1
- GutGard® significantly lowers the symptoms of daily digestive health problems (upper abdominal fullness, belching, regurgitation, upper abdominal pain, nausea, bloating, and vomiting)
- GutGard® improved quality of life
Clinical study 2
- 48% of the population in the GutGard® group were relieved from H. pylori as assessed by 13C-UBT

Clinical Study 1
- GutGard® effectively managed the symptoms of Functional dyspepsia (upper abdominal fullness, belching, regurgitation, upper abdominal pain, nausea, bloating, and vomiting)
- GutGard® improved quality of life
Clinical Study 2
- GutGard® showed 41% reduction in H. pylori load compared to placebo
- 48% of the population in the GutGard® group were relieved from H. pylori as assessed by 13C-UBT
Randomized double-blind, placebo-controlled clinical study in subjects with Functional dyspepsia.
Raveendra et al. Evidence-Based Complementary and Alternative Medicine 2012,Article ID 216970, 9 pages, 2012.
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Effects of GutGard® on Functional Dyspepsia
Randomized double-blind, placebo-controlled clinical study in subjects with H. pylori
Puram et al. Evidence-Based Complementary and Alternative 2013, Article ID 263805, 8 pages, 2013.
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Effects of GutGard® on H. pylori
GutGard® pre-clinical research
GutGard®: Mechanism of action
Works against H. pylori (in vitro inhibited H. pylori protein synthesis, DNA gyrase and dihydrofolate reductase)

Health benefits
150mg per day
Helps manage daily gut health issues - upper abdominal fullness, upper abdominal pain, nausea, bloating, belching & regulations*
Promotes daily gut health*
Relief from meal triggered indigestion*
Support management of H. pylori*
Dosage*
150 mg per day
Applications of GutGard®
Probiotic count (cfu/ml)


- GutGard® added to probiotic drink (Lactobacillus acidophilus)
- This indicates GutGard® is compatible with tested probiotic drink
- Probiotic count remained at the acceptable level


GutGard® can be combined with the Digestive Enzymes






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